Selected Publications
Digital Development: A database of C. elegans cell lineage differentiation with lineage phenotypes, cell-specific gene functions and a multiscale model.

Santella A, Kovacevic I, Herndon L, Hall D, Du Z*, Bao Z*.   
Nucleic Acids Res. 2016 Jan 4;44(D1):D781-5.
The regulatory landscape of lineage differentiation in a metazoan embryo.  

Du Z*, Santella A, He F, Shah PK, Kamikawa Y, Bao Z*.  
Dev Cell. 2015 Sep 14;34(5):592–607. (Free Featured Article)
POS-1 promotes endo-mesoderm development by inhibiting the cytoplasmic polyadenylation of neg-1 mRNA.  

Elewa A, Shirayama M, Kaymak E, Harrison PF, Powell DR, Du Z, Chute CD, Woolf H, Yi D, Ishidate T,  Srinivasan J, Bao Z, Beilharz TH, Ryder SP, Mello CC.  
Dev Cell. 2015 Jul 6;34(1):108-18.

E3 ubiquitin ligases promote progression of differentiation during 
C. elegans embryogenesis. 

Du Z, He F, Yu Z, Bowerman B, Bao Z.  
Dev Biol. 2015 Feb 15;398(2):267-79.

De novo inference of systems-level mechanistic models of development from live imaging-based phenotype analysis. 

Du Z, Stantella A., He F., Tiongson M, Bao Z. 
Cell. 2014 Jan 16;156(1-2):359-72.
Systematic quantification of developmental phenotypes at single-cell resolution during embryogenesis. 

Moore JL, Du Z, Bao Z. 
Development. 2013 Aug;14 (15):3266-74. 
Inverted selective plane illumination microscopy (iSPIM) enables coupled cell identity lineaging and neurodevelopmental imaging in Caenorhabditis elegans. 

Wu Y, Ghitani A, Christensen R, Santella A, Du Z, Rondeau G, Bao Z, Colón-Ramos D, Shroff H. 
Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17708-13.
Single-molecule analysis reveals changes in the DNA replication program for the POU5F1 locus upon human embryonic stem cell differentiation. 

Schultz SS, Desbordes SC, Du Z, Kosiyatrakul S, Lipchina I, Studer L, Schildkraut CL. 
Mol Cell Biol. 2010 Sep;30(18):4521-34.

Genome-wide colonization of gene regulatory elements by G4 DNA motifs.  

Du Z, Zhao Y, Li N.
Nucleic Acids Res. 2009 Nov;37(20):6784-98. 
Genome-wide analysis reveals regulatory role of G4 DNA in gene transcription. 

Du Z, Zhao Y, Li N. 
Genome Res. 2008 Feb;18(2):233-41. 
* Corresponding Author
Copyright © The Du Lab, All Rights Reserved. Updated on Nov 2016
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