WormBase ID: WBGene00001961 WormBase description: Is an ortholog of human BHLHE23 (basic helix-loop-helix family member e23). Is predicted to have protein dimerization activity. Is involved in positive regulation of dopaminergic synaptic transmission and positive regulation of transcription by RNA polymerase II. Is expressed in CEPshDL; CEPshDR; CEPshVL; CEPshVR; and ventral cord neurons. Human ortholog(s) of this gene are implicated in congenital malabsorptive diarrhea 4 and persistent hyperplastic primary vitreous. |
Reporter verification: Verified by PCR and sequencing |
Strain name: SYS585 Cross: OP643 x JIM113 Strain genotype: ujIs113 (pie-1p::mCherry::H2B; nhr-2p::mCherry::his-24::let858 3'UTR; unc-119(+)) II; wgIs643 (hlh-17::TY1::EGFP::3xFLAG + unc-119(+)) |
Expression pattern: Expressed after bean stage |
Lineage expression pattern 350 stage ![]() ![]() |
600 stage ![]() |
3D expression pattern ![]() 4-cells ![]() 8-cells ![]() 15-cells ![]() 28-cells ![]() ~50-cells ![]() ~100-cells ![]() ~200-cells ![]() ~350-cells ![]() ~500-cells ![]() ~600-cells ![]() 600-cells ![]() bean-stage |
Inferred TF relationships Based on expression similarity (strong, medium, weak): NA Based on ChIP-seq (directly from ModERN database, targets from L1 stage ChIP-seq data are underlined) Targeting: no-data Targeted by: NA |
Targeting: no-data Targeted by: NA |