microRNA name: miR-124

WormBase ID: WBGene00003319

WormBase description of miR-124: Is expressed in nervous system and tail. Is used to study Werner syndrome. Is an ortholog of human MIR124-1 (microRNA 124-1); MIR124-2 (microRNA 124-2); and MIR124-3 (microRNA 124-3).

Conserved microRNA sequences of miR-124:

D.melanogaster: dme-miR-124

H.sapiens: hsa-miR-124, hsa-miR-506

Location: intron sense

Promoter length (bp): 3230

Promoter sequence: ACAGGCGTAGGTGACTTTGCCTCTTTCAAAACAATGATTCACCAGTATCCTAACCTGATTTTGAATCCTCCTTCTTACTAATTAGGACTATACTAGACAGGCTTCACGTTTTTGAAAATGCTCGACGGTTAATCTGGGTTCCACGTAATTTTCGGATCAACCATAGCGGCATGGTTAGATGTTCATTTGCACCTGCAATTAGTCACCGTTTCCCCCAAAATTTTCCCGTATCCTCTCTTCCCGGTTTGTCTGATCTTCATCACATCTGCTCATGGTTCTTACGAAACACGAAGCTTCTAATGAAGGGGGCCCTCCCATCAATTATAGGCTTTGAGCGAGAAAAAGATTTTGGACAACCGTGCGGTATCTTGTGCTCAAAAAAAAATCCCCACCGTGTCCAATGCTAATTGCTATCTAAAATATATGCATATATGGGCACCAAGTTGTTTACGTGAAAGAGCGTATTTTGGAGATATAATTCGAGAAAAGAAGATTATTGTTGTCAACAGGCAATCTCATAGGCTCATAGGGGTGGTTTTGAAAAATGGACATATGCTAAAGTATACGACAAGTTAAGTAATACGTTTAGATTTGGGCTGGGTATTACTAGAAGTTTCATGTACTTAGCATAGCCAACATGCTTGCCTACAAGGCATGCTTGACTCTTCTGGAAGGTGCTCCGTATTAGCAGCGAAGAAAGTCATGAGTCCTTATTTCTGTAGATCAAATCAACCTAAACGTTACAGGTCTCTTTTGAAGCAAGTTATGCCTGTAGGCGGACGGGCTTGCCTACAGGTCGACATGCTTATACATGGGCCTATAGGAACCTACACGAGAGTTGTCAATTTTCAGAAATTTCTACTCTCGAAAATTACATCACGAGCTATCAGGTTGTCCCATAAGTTTTTGTACTTTTTTTCAAATATTTTTCCAAAACTTCTAGAAAGTTTTAAAATTTTTTCATCGTAGGTCGTGTCAAGGTCGGGTCGTCCCCTTTCAGAAAAGATTCATTTCATCCATTTCTACTTTGCCACGATGACAATCATCAAACTTGAACGTCGAGACGTTAGATTGCTTCTTCTTTATGAATTTCGTCTTGGTCATTCAGCAATGGAAGCGGAACGAAACATATGCGGTGCGATGGGTGAGGGAGCACTCTCTTATAATACAGCAAAGAGTTGGTTTCAAAAGTTCAAGAACGGCGACTTCAGTCTCGAAGAAATAGAACGTTCTGGGCGACCGATAGAGTTAAATGAAGAAGACCTAGTGAAGCTGGTGGAGGAAGAGCCTCGTCTTAGTCTTCGTGAAATGGAAGAGAAGCTTGAGTGTTGTCATAGCACAATTGCACGTCACTTGGGTCGCCTTGGTTTTACTTCAAAACTTGGAATTTGGGTGCCTCATGAACTTTCGGCATCACAGAAGCTCACTCGGGTCAACGTTTGTACTCAACTTCTAACTTTTCGTCGAAAGTTCGATTGGCTGAACAATCTGGTTACTGGAGATGAGAAGTGGGTGCTCTATGTTAACCATTCCAGAAAACGTCAATGGCTTCCGATCGGTGAGAAAGGAATACCGACGCCAAAGCCTGATCTTCACCCAAAAAAGATTATGATCTGTGTCTGGTGGGGTGTTCAAGGACCCGTGCACTGGGAATTGTTGCCAACTAATAAAACTATCACTGCTGATTACTATTGTGCCCAATTGGACCGAGTTGCAGAAAAGACCAACGGAAAATATGAAAAACTATATTTTCTTCACGATAATGCTAGGCCTCATGTCGCCAAGAAGACTTTCCAAAAGCTGCAAGATCTTGGTTGGACTGTTTTACCGCATCCACCATATTCTCCAGATCTTGCACCAACCGACTACCATTTGTTCTTGTCTCTCAGTGACTACATGCGCGACAAGCAATTCGACGACGAAGAGCATCTCAAAACTGAACTCTCCACTTTCTTCTCATCGCGTTCGCCGGATTTCTTCTCCCGTGGCATCATGATGTTACCTAGTAAATGGCAACAAGTGGTGGACACTAATGGTGAATACTTGTGTGAATAGTACTACTTGTCGCTTGAGAGAAATAAATTTTTTTCAAAAAAAAATAGTACAAAAACTTATGGGACAACCTGATATTTAATTTCTCTATCAGTGTTATTATCGTGTGTAAGCCAAAAAAGTGATGTTGGCTGCAAATAATTTATTGGAGAATCCAGAGTTTTCCCTGTGCACTTGATTCTGGACCCATCGAGAAAGTGAACATGTGCTTTAACGAAATACATCACATTTTCTCTTTCCTATTCATGTGCCTACAATAACAAAGTTGCACCTACTCTGTAGGTATGCAGGTACGCACACCATTGAAAAAAGGTTTTTGGATGCTTCCATAATGTAATTAACTTTTAAAGAATTCACTTTTGCGTCTGTTGTCACACATGACAAAGTCCCTATCTCCCCTTCCATGCTCCAGACAGCAACCACCAGTTGATAACATTTCAATACTTTTCTTTTCTATCTGTTACTTTTATCCTCCACTGTTTTTATGCTCTCTGAGCATCTACAGAAGTAGAACTTGGCGCCGTGCGTCTATCGATTTTCGTTGACGGGCCCCCGCGGTCTATCTGCGCAATTCTCGAAGTCGAGTCTCCACAGATTCAATACTATCTCATCTCGGTGCTCACGTCGTCTAGCACGAAGCCGTCCTCCGCCTTCCCCTTTCCTTTTTCGTTCTCTTCTTTCTTCTTTCTTCTCATTCGCAGTCCGTTGCTGTCGCCGACGCCGCCGCGGCTCTTGACTAGTAACCCGCTCTCTTCTACCAAACAACCAGTATTCATGCTTTGCTTCTTCTTCGAGCACACAGGAGGCATGTAATCTCTCCGGTGAACCACCTGCCTTGGCTTCCCCTAGGCACCATGGCAGTCTAATCCAGAGCGAGAGAGAGAGAAAAGACCTCCTCCTTCTCTCTCTCTCTCTCTCTACCACCTGCCCAAATGAGAAATGACTCCGCCCTCGTCGCTCATTGATTCACATCCATTTTGAGAAGGATGGTTGCTACTGCTGCTTGATCTCAAGGACTGTGTGCTCCCACTTTTACTCAAAGTATTTTATTTCTTCTTCAAGTGCTCTCTTCTCCATTTTTGAATTTCCTTCGCAATTGATACACCATGTCCCACTTGTCATCTGGCATGCACCCTAGTGACTTTAGTGGACATCTAAGTCTTCCAACTAAGGCACGC

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Tissue specificity (embryo): Neuron

Tissue specificity (L1): Neuron

Number of insertion lines: 5

All strain names: SYS1769, SYS1770, SYS1771, SYS1774, SYS1780

Representative strain name: SYS1769

600-cell stage and L1 stage
The black dots on the lienage tree represent an increase in the fluorescence intensity of miRNAp::mNG::H2B during this cell cycle.

Embryo

L1

Embryonic 3D expression pattern

4-cell

8-cell

15-cell

28-cell

~50-cell

~100-cell

~200-cell

~350-cell

~500-cell

~600-cell

600-cell

bean-stage

L1 3D expression pattern

Left view

Right view

Dorsal view

Ventral view