microRNA name: miR-1

WormBase ID: WBGene00003260

WormBase description of miR-1: Is expressed in body wall musculature; muscle cell; and pharyngeal muscle cell. Is used to study Parkinson's disease.

Conserved microRNA sequences of miR-1:

D.melanogaster: dme-miR-1

H.sapiens: hsa-miR-1, hsa-miR-122, hsa-miR-206

Location: Intergenic

Promoter length (bp): 3799

Promoter sequence: TCAAACAAGATTTCTTACATTCGGATCGGTCAATTGGAGATCCAGCTTCAAAAATGATAGATTCACATTCCGGCGGGCTTTCTTCACATGTTTCATCGTAATTTTCAGAGTCACTCTCATCCGGCATCATAAGCTTGTTTTTTCACTTTCGAAAAGTTTAAATGAACAATAAATTTGAAATGAATCATTATTATGATTGCCTGACGTTTTTTTATCGTTTTTTTTTCATGCTGTTCTGTTTTAATTTCGTCACGTCTAAAAATAAACATATCAACCCTTGAAGCTGGAGTGTCGACTGTTGAACTTACAGTATTCCTCTAGATTTGAAAGATATTGTTGAATTGAGACTATAAAAATTGCAATAAATTTTGGGAAGTGACTTCGAGAGAGAGATTTAAGAAAAAAGTCTGGAAAAGATTCAATTGTAATTGCCATGTTTTATTTATAAATAAATAATTCAATTAAAAAAATTAAAGCCTTTTCATTGTGAAATTTGCACATGTTCACAATTGAATTTTTCGAACAATTTTGGAAAATGTTTTATGTCGAAATCTTATTAAAACTCAGTTTGTGCCACTTTTTTTAGAAATCTAAAGAACTGTCGAACCCCCACAATGTTCGGATTCGGATATTTTAAAATACATAACACTGAAATAATTTATTTTTTGATCGACGACTTCTAAAAAATAAGTGAAAACTTGACATTTTCCCCAAATTTTATGAAAAGTTTCATTATGGTATTTGTTCATTTTGGCACAAAAGAAATGGTTTTCAATCATTTCACAACTGGCTGTACTTCAGCTTTAGTTGGGTAAATACGGTATATGTCAAAAATGGGGAAATACTAATTGTAAAAGAGGAAATATGGTTGCTACAGTAATCTTTAGAAGAATTATGATCAATAGGATATATTTCACATCCTTCGAACTTCTTCCTCCTCCCACACTATTTTCCTGGATTTTGCAAATTTAAAACACACACATACACACACAAAATGAGGTACGCACAGGAAAAACCCTTTCTTCCTGATTTCAATGACTTTTTCTTCTGTTTCTTCTCTTCTTTTGCTCAACTGGCTCTTCACTGGGGTCTTAGTAGGAGAGCCCCGACGGGAGCCCTTCTATTCTTCTCCGTCTCTTCATTTCTCATCCTCTCTGTGTTCCCACAAGAGATTTTTGTCCGTGAGAGTACCACGAGGCATACGGTAGGCGATTGGAGGCAGAAAAGACTTAGAGCACAAATGTGCACTCGGGGCGCGCTCTTCACGGTTTACAGTCCTCCCACACGACGAAGAGGCATAGAGAAATCATTTTCTTATGTTCTCTAAATCTCTTGTTACACATTGAGAGCTCTAGAGAGTCGAGTACCTCCTACCCGTCCCAAAAATTGGAGAGTAAGGATAAATGAAGAGAGTTCTAGACACGCTGACAGTTTGCCAAAGTTCACAGATTGTCTCTTCAAAGAAGAGTGGCGGGAGGTCTCTCTCTTCAATGAAGAAGCGCCCCCGGAGAAAAGATGTACACGATCATTGAGAGTTGGCAGAGATGGCAGAGAACGGATAAAAACACGTTCGGAGCATTGCGATCTGGGATCCGAAGAGCCTTTGAGGAAGAGGAAGAAGAAAAATAGAAGATGATCGATTGCGAGGGAGGATATAATCACGGATAGGTGTTCACTTTAACACCAAAAATCGGTGATTGATTGAAGGTAATTAATACTTTTCAAGTGGTTTTCAAGATACAAATCTTGATGACATCTGCAAGAAACTTTAAATTTAAAAAAATGTTGCAGGAAAAAGCTAAAAGCAGCGGGCGATTTGGGTTAGAAAATAAATACTAAACTTAGGAAGCTCAAATCTAGATGTTTTCTATATTATAAAAGTTAGAAGCAGATAAAAGATATCACCTATATTCTATCACTTGGAGTAGCGCCAGTTTTTTTCTCAATTTTTACAAATTACGCTTCAATAGATCAAAAAATGAAAAGCTTATACTTCGAAATGCTCACGAAATTCTTGCCTATTCAAACCCTAAAACATACAAGGAACTAATTACTTTTTTGTGGTCGGTTTCCAAAATTATGATAAGTTCTTCAACATTAACTTTAACGTCCCTAATATTATGAACACATATAAACCGATCAGATTTTGTGTTACATTTAGGAACCAACATAAACATTGGTATTTTACAATAACTTTAACCTGAACCAATGAATTCAATCTAAAGTACTACTGCTTCACCAGTACATTTCATAAAACCAACAATCAATGTGTACAGAAAATCATAAGTTTCCTGAATGTTTCTCATTCAACATCTAACAGCTGAAAACCGGAAACTGTCTGTTATTATGTGTAGAAAAAGGGAAGAGACTTTTTCCTCCACCTACTCTTGATATACTACTTTCTATAAATTGTTTCAAAAAGGCGATATTGATTAAATACTCGGCACTACAACAGAATCAATTATTGATTATTTATTTTCCTTTCAGTGGTATTACTCGTTGGGAGTTCGTATTCATATTTTTTAGAAATAATTCGCTCACAATTTTTTATAAATTCTAAAAAACCCGACAACATAGAAATGGTAACTGTATCAAATGTTTTTAAAAAAAACGAACAGACTTATTTACTGTCCAAATTCAACAATTTTTGTTTTCGCGAAACCAAACATTTTTCTGCAATCCCATACCGATCCTACCATTTCAATTCCTCCGGAAATCCTCGTTCCTAGCCATGGCCAAAAAATCAAAAGCTTTATAGAAATTCTGAGAAATTATTGAATATATTCTGTGCTAGTTCTTCGCAGAAGTTTGGAATTTTACGAACTACAAACATGAGATATGAGCATTAAAAGTTTATGAACCCTAGCGAGATTGTTTAGAAATACTAAATATTGCTCACAAATAGCAATTTTTCAAAAATTAATTTTATTCCTCTTTACCATATCCAATTAATTCTTTGGAGATCTTAATTACAAAAGACCCTGACCTATCTCTTTCACCCATATCAGATTTCATTGAAATTATTACAGTAGTCTTTGAACATCTGTGACTCTCAAACTCTTATAATCTCTTACAATTACTTGTTTCGCCTGGCTCCAACTCTACTGTACAACCAACTCTCTTTTCCCTCCTCCTCATCCTACTCAGAGAGAAAGAGAGAAATGGGAAAAGGTACGCCTCCTTCCAAAAAATAGGCGGAGTCTGGGAAGGACAAGAAGAAGCAGCGAGAAGCCAGTCCCTACACCCAAACCAACCGAAAGACATTCTTCCGATCATTCTCGCTCTCTCTAGTTCTCTTCCTCGTTTTCTTTCTCTCTTCTTCTTTTTAAATATCGCCAATTTTTCCATTCGATGCCTGTTAAGACGGCAATGACGGAGGAATGAGTAGAAAAAGACGAAGAAGAGAGGCCTCTCTGTACGTGTGCAAATATATTTGCTCAGTGCGCACGCACCTTCTTTTCTTAGGTCGAACCCCACCCATCCTCTCTACAAATCTCCCGCTACCTTCATACAAACACACTGTAGACTTACTTGGTTCAAGTTCCAAGTTACTATTGGGTTTAGTCTTACGTTCATTTGTGTAGTAGTCACTTACCATACTAAGTTGATTGGAGAAACTTATTGTAGAGAAGAGAGTGTAAGCTGATTTAAACTTCTCTTCAACTCTCCGAAGAATTTTTTGATCTCCCAAATCTTTCACGAGTCGTCTTTTCCCAGATTCAATTCTACTCTATATCTACGCTATATTCAAAGTGACCGTACCGAGCTGCATACTTCCTTACATGCCCATACTATATCA

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Tissue specificity (embryo): Pharynx, Muscle

Tissue specificity (L1): Pharynx, Muscle

Number of insertion lines: 3

All strain names: SYS1686, SYS1755, SYS1756

Representative strain name: SYS1686

600-cell stage and L1 stage
The black dots on the lienage tree represent an increase in the fluorescence intensity of miRNAp::mNG::H2B during this cell cycle.

Embryo

L1

Embryonic 3D expression pattern

4-cell

8-cell

15-cell

28-cell

~50-cell

~100-cell

~200-cell

~350-cell

~500-cell

~600-cell

600-cell

bean-stage

L1 3D expression pattern

Left view

Right view

Dorsal view

Ventral view