microRNA name: miR-259

WormBase ID: WBGene00003353

WormBase description of miR-259: Is affected by several genes including daf-12; eat-2; and prg-1 based on tiling array and RNA-seq studies. Is affected by four chemicals including nicotine; multi-walled carbon nanotube; and graphene oxide based on quantitative PCR; RNA-seq; and microarray studies.

Conserved microRNA sequences of miR-259:

D.melanogaster: dme-miR-304

H.sapiens: hsa-miR-216a, hsa-miR-216b

Location: Intergenic

Promoter length (bp): 1257

Promoter sequence: actttaaaagtcttctggaaaaagtggcgacgttttcgtgaccaaatggcatctttgtaatcgagacaccgtcaacggaagtatttcggttacaccgatttttcatcactgctactgctgctctcttctttttcgatctgtggtgtagtgcaacaaggagccagattgtctttcaatctgggaatagaaaaatgcattgcagacatctgaagatacattcaaatgattcacaaaaaatatattcgagaatgtgtaagatcacgtttctatgatagaatggagtttgtgtgataattcatgaattggaagtacaatattaaagttatgtttccagatcattaggaatgtatcttatcactatcatcattgatgaaaattggtctttttgatgtaaaagacatcaacaagagtaaacggagttgttattatgtagacgtttgaagatcagaacttctgccatgtcttcatctcggcacgtggatctcgagttactgtaccttaaaaccgatatatttagatatttacgtactaaaattttttaaatgaatgtttaaattcaaaatagaaaaaaaccgaatcaattgattaaattctttccaaaatgggttttttgtattttaatccaaaatcaaacaagtttgtttaaaacgttttttatgttctaattgtagttttgttgatagctctgaaaaatgcaagtttttcaagtggggaaatttaagttgagagaatatttagattgaaaattgtcttttaatgctgtcttattgtcattaattcaacattaaaaattcattaaattcctttattattataacgtgaaatttcagaaattcaattcatttcattaagttacctattaatacgaatgatttattatcagcacatttttcgaattcccgtcgggaaacgtgtgctaatccgttgaatgtgtacatgcgccttttctctgtcatcaagagggctgtaagtactatttgaacaaggagcggcactgttatgaccgcttttggaccgactcagattcaacaattccttattcctagcattgaaccttatttgtgtgttcgttctcatatcaactaaagaagtgagcaaagaaggaggagactgtactttcgctcttgtatgctaaaacatgacgcataagacagtgacgaatgtttcttcctttcttttttcttattcttcacttgttcatttctttacttctgctcagaatagtacatagtggtaagttcggtT

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Tissue specificity (embryo): Rectum & anus

Tissue specificity (L1): Pharynx, Intestine, Rectum & anus

Number of insertion lines: 2

All strain names: SYS1466, SYS1467

Representative strain name: SYS1466

600-cell stage and L1 stage
The black dots on the lienage tree represent an increase in the fluorescence intensity of miRNAp::mNG::H2B during this cell cycle.

Embryo

L1

Embryonic 3D expression pattern

4-cell

8-cell

15-cell

28-cell

~50-cell

~100-cell

~200-cell

~350-cell

~500-cell

~600-cell

600-cell

bean-stage

L1 3D expression pattern

Left view

Right view

Dorsal view

Ventral view