Summary

Gene name
cdc-25.1
Sequence name
K06A5.7
Gene ID
WBGene00000386
Gene type
Protein Coding
RNAi library location
I-3I13
Gene information
Is an ortholog of human CDC25A (cell division cycle 25A)\; CDC25B (cell division cycle 25B)\; and CDC25C (cell division cycle 25C). Is predicted to have protein tyrosine phosphatase activity. Is involved in meiotic spindle organization and positive regulation of mitotic cell cycle. Localizes to the nucleus. Is expressed in several tissues, including the embryonic cell and the germ line.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A/P)		 Cell
position		 Phenotype
detection
CDC-25.1_emb1 61 66 21 2 37 560
CDC-25.1_emb2 171 Global proliferation rate changed Global proliferation rate changed 58 41 338
CDC-25.1_emb3 166 Global proliferation rate changed Global proliferation rate changed 40 53 350
CDC-25.1_emb4 170 Global proliferation rate changed Global proliferation rate changed 65 56 344
CDC-25.1_emb5 174 Global proliferation rate changed Global proliferation rate changed 54 36 331
CDC-25.1_emb6 169 Global proliferation rate changed Global proliferation rate changed 38 27 326
With cellular defects Yes Yes Yes Yes Yes Yes

Early embryonic arrest

Arrest embryo: CDC-25.1_emb7, CDC-25.1_emb8

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

Abnormal division asynchrony
Not analyzed
Normal

Division asymmetry(A/P)

Larger division asymmetry
Smaller division asymmetry
Not analyzed
Normal

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle(A/P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal