Summary

Gene name
cdt-1
Sequence name
Y54E10A_156.a
Gene ID
WBGene00000413
Gene type
Protein Coding
RNAi library location
I-7J20
Gene information
Is an ortholog of human CDT1 (chromatin licensing and DNA replication factor 1). Is predicted to have DNA binding activity and DNA polymerase binding activity. Localizes to the chromatin\; cytoplasm\; and nucleus. Is expressed in the anchor cell\; the germ line\; and the vulD. Human ortholog(s) of this gene are implicated in Meier-Gorlin syndrome.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
CDT-1_emb1 131 Global proliferation rate changed Global proliferation rate changed 7 18 84
CDT-1_emb2 109 Global proliferation rate changed Global proliferation rate changed 11 14 189
CDT-1_emb3 87 Global proliferation rate changed Global proliferation rate changed 9 9 130
With cellular defects Yes No No Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal