Summary

Gene name
ced-12
Sequence name
Y106G6E.5.1
Gene ID
WBGene00000426
Gene type
Protein Coding
RNAi library location
I-9A09
Gene information
Is an ortholog of human ELMO1 (engulfment and cell motility 1). Exhibits Rho GTPase binding activity\; phosphatidylinositol phosphate binding activity\; and proline-rich region binding activity. Is predicted to contribute to guanyl-nucleotide exchange factor activity. Is involved in several processes, including actin cytoskeleton organization\; apoptotic process involved in development\; and phagocytosis. Localizes to the cytoplasm\; guanyl-nucleotide exchange factor complex\; and plasma membrane. Is expressed in the intestinal cell and the tail.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
CED-12_emb1 0 0 0 0 2 1
CED-12_emb2 0 0 0 0 1 154
With cellular defects No No No No No Yes

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

Abnormal cell position
Not analyzed
Normal