Summary

Gene name
cye-1
Sequence name
C37A2.4
Gene ID
WBGene00000871
Gene type
Protein Coding
RNAi library location
I-3G06
Gene information
Is an ortholog of human CCNE1 (cyclin E1) and CCNE2 (cyclin E2). Exhibits cyclin-dependent protein serine\/threonine kinase regulator activity. Is predicted to contribute to protein kinase activity. Is involved in several processes, including DNA endoreduplication\; regulation of cellular protein localization\; and regulation of mitotic cell cycle. Localizes to the chromatin and nucleus. Is expressed in several tissues, including the G cell\; the epithelial system\; the reproductive system\; the ventral cord blast cell\; and in the male.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A/P)		 Cell
position		 Phenotype
detection
CYE-1_emb1 110 29 6 1 2 10
CYE-1_emb2 128 Global proliferation rate changed Global proliferation rate changed 7 3 4
CYE-1_emb3 153 Global proliferation rate changed Global proliferation rate changed 0 0 4
CYE-1_emb4 267 Global proliferation rate changed Global proliferation rate changed 0 7 57
With cellular defects Yes Yes Yes Yes Yes Yes

Early embryonic arrest

Arrest embryo: CYE-1_emb5

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

Abnormal division asynchrony
Not analyzed
Normal

Division asymmetry(A/P)

Larger division asymmetry
Smaller division asymmetry
Not analyzed
Normal

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle(A/P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal