Gene name

daf-16

Sequence name

R13H8.1

Gene ID

WBGene00000912

Gene type

Protein Coding

RNAi library location

I-5M24

Gene information

Is an ortholog of human FOXO1 (forkhead box O1)\; FOXO3 (forkhead box O3)\; and FOXO4 (forkhead box O4). Exhibits several functions, including 14-3-3 protein binding activity\; DNA-binding transcription factor activity\; and enzyme binding activity. Is involved in several processes, including defense response to bacterium\; regulation of cellular biosynthetic process\; and regulation of post-embryonic development. Localizes to the cytosol and nucleus. Is expressed in several tissues, including the alimentary system\; the epithelial system\; the muscular system\; the nervous system\; and the reproductive system. Is used to study Parkinson's disease. Human ortholog(s) of this gene are implicated in alveolar rhabdomyosarcoma.