Summary

Gene name
daf-8
Sequence name
R05D11.1
Gene ID
WBGene00000904
Gene type
Protein Coding
RNAi library location
I-4O23
Gene information
Is an ortholog of human SMAD6 (SMAD family member 6) and SMAD7 (SMAD family member 7). Exhibits RNA polymerase II transcription factor binding activity. Is involved in several processes, including dauer entry\; defense response to Gram-negative bacterium\; and regulation of cellular biosynthetic process. Localizes to the cytosol and nucleus. Is expressed in the excretory cell\; the gonad\; the intestine\; and the nervous system. Human ortholog(s) of this gene are implicated in aortic valve disease 2.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
DAF-8_emb1 0 0 0 0 0 0
DAF-8_emb2 0 0 0 0 0 0
DAF-8_emb3 0 0 0 2 0 0
With cellular defects No No No No No No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

No defects