Gene name

dhc-1

Sequence name

T21E12.4

Gene ID

WBGene00000962

Gene type

Protein Coding

RNAi library location

I-1P04

Gene information

Is an ortholog of human DYNC1H1 (dynein cytoplasmic 1 heavy chain 1). Is predicted to have several functions, including ATP-dependent microtubule motor activity, minus-end-directed\; dynein intermediate chain binding activity\; and dynein light chain binding activity. Is involved in several processes, including GABAergic synaptic transmission\; cytoskeleton-dependent intracellular transport\; and generation of neurons. Localizes to the cell cortex\; intracellular non-membrane-bounded organelle\; and nuclear envelope. Is expressed in germ cells\; the head\; the somatic cell\; and the tail. Is used to study lissencephaly. Human ortholog(s) of this gene are implicated in Charcot-Marie-Tooth disease axonal type 2O and autosomal dominant non-syndromic intellectual disability 13.