Summary

Gene name
drh-3
Sequence name
D2005.5
Gene ID
WBGene00008400
Gene type
Protein Coding
RNAi library location
I-3H24
Gene information
Is an ortholog of human DHX58 (DExH-box helicase 58). Exhibits RNA binding activity\; RNA polymerase binding activity\; and RNA-dependent ATPase activity. Is involved in P granule assembly and production of siRNA involved in RNA interference. Localizes to the P granule\; condensed nuclear chromosome\; and metaphase plate. Is expressed widely.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
DRH-3_emb1 0 0 0 1 0 0
DRH-3_emb2 0 4 0 0 0 0
DRH-3_emb3 0 1 0 1 1 3
DRH-3_emb4 334 Global proliferation rate changed Global proliferation rate changed 17 7 403
DRH-3_emb5 329 Global proliferation rate changed Global proliferation rate changed 50 72 659
DRH-3_emb6 270 Global proliferation rate changed Global proliferation rate changed 112 48 481
DRH-3_emb7 341 Global proliferation rate changed Global proliferation rate changed 2 7 44
With cellular defects Yes Yes No Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

Abnormal division asynchrony
Not analyzed
Normal

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal