Summary

Gene name
elpc-1
Sequence name
Y110A7A.e
Gene ID
WBGene00022463
Gene type
Protein Coding
RNAi library location
I-2C20
Gene information
Is an ortholog of human ELP1 (elongator complex protein 1). Is predicted to have tRNA binding activity. Is involved in several processes, including embryonic morphogenesis\; gamete generation\; and olfactory learning. Localizes to the cytoplasm\; neuron projection\; and neuronal cell body. Is expressed in the nervous system\; the pharynx\; and the reproductive system. Is used to study Riley-Day syndrome. Human ortholog(s) of this gene are implicated in Riley-Day syndrome.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
ELPC-1_emb1 353 Global proliferation rate changed Global proliferation rate changed 3 0 0
ELPC-1_emb2 353 Global proliferation rate changed Global proliferation rate changed 0 0 0
ELPC-1_emb3 353 Global proliferation rate changed Global proliferation rate changed 4 0 0
ELPC-1_emb4 1 0 1 0 0 0
ELPC-1_emb5 0 0 1 0 2 13
With cellular defects Yes No No Yes No Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

Abnormal cell position
Not analyzed
Normal