Summary

Gene name
exos-3
Sequence name
F59C6.4
Gene ID
WBGene00010325
Gene type
Protein Coding
RNAi library location
I-5C20
Gene information
Is an ortholog of human EXOSC3 (exosome component 3). Is predicted to have RNA binding activity. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene are implicated in pontocerebellar hypoplasia type 1B.

Lineage tracing results

Phenotype

Cell
cycle
Division
asynchrony
Division
asymmetry
CND-1
expression
Division
angle
(A-P)
Cell
position
Phenotypic
measurement
Phenotypic
detection
EXOS-3_emb1 284 Global proliferation rate changed Global proliferation rate changed 10 0 0
EXOS-3_emb2 273 Global proliferation rate changed Global proliferation rate changed 0 0 0
EXOS-3_emb3 0 2 0 0 4 0
With cellular defects Yes No No Yes Yes No

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

No defects