Summary

Gene name
goa-1
Sequence name
C26C6.2
Gene ID
WBGene00001648
Gene type
Protein Coding
RNAi library location
I-3P15
Gene information
Is an ortholog of human GNAO1 (G protein subunit alpha o1). Exhibits several functions, including G protein-coupled acetylcholine receptor activity\; GTP binding activity\; and GTPase activity. Is involved in several processes, including defense response to Gram-negative bacterium\; dopamine receptor signaling pathway\; and negative regulation of axon regeneration. Localizes to the cell cortex. Is expressed in the alimentary system\; the muscle cell\; the nervous system\; the reproductive system\; and the tail. Human ortholog(s) of this gene are implicated in early infantile epileptic encephalopathy 17.

Lineage tracing results

Phenotype

Cell
cycle
Division
asynchrony
Division
asymmetry
CND-1
expression
Division
angle
(A-P)
Cell
position
Phenotypic
measurement
Phenotypic
detection
GOA-1_emb1 0 0 1 0 4 0
GOA-1_emb2 0 0 1 0 11 266
GOA-1_emb3 0 0 0 1 5 243
With cellular defects No No No No Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal