Summary

Gene name
gon-2
Sequence name
T01H8.5
Gene ID
WBGene00001651
Gene type
Protein Coding
RNAi library location
I-4O21
Gene information
Is an ortholog of human TRPM1 (transient receptor potential cation channel subfamily M member 1). Is predicted to have cation transmembrane transporter activity. Is involved in defecation\; gonad development\; and mitotic cell cycle. Is expressed in the gonad and the intestine. Human ortholog(s) of this gene are implicated in intestinal hypomagnesemia 1.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
GON-2_emb1 139 Global proliferation rate changed Global proliferation rate changed 2 0 0
GON-2_emb2 174 Global proliferation rate changed Global proliferation rate changed 11 12 149
GON-2_emb3 241 Global proliferation rate changed Global proliferation rate changed 0 0 0
With cellular defects Yes No No Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal