Summary

Gene name
gpi-1
Sequence name
Y87G2A.q
Gene ID
WBGene00013597
Gene type
Protein Coding
RNAi library location
I-6L08
Gene information
Is an ortholog of human GPI (glucose-6-phosphate isomerase). Is predicted to have glucose-6-phosphate isomerase activity\; intramolecular transferase activity\; and monosaccharide binding activity. Is expressed in the head. Is used to study Parkinson's disease. Human ortholog(s) of this gene are implicated in congenital nonspherocytic hemolytic anemia.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
GPI-1_emb1 320 Global proliferation rate changed Global proliferation rate changed 21 86 621
GPI-1_emb2 280 Global proliferation rate changed Global proliferation rate changed 41 59 542
GPI-1_emb3 50 Global proliferation rate changed Global proliferation rate changed 2 18 79
With cellular defects Yes No No Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal