Summary

Gene name
him-1
Sequence name
F28B3.7
Gene ID
WBGene00001860
Gene type
Protein Coding
RNAi library location
I-2O07
Gene information
Is an ortholog of human SMC1A (structural maintenance of chromosomes 1A). Exhibits DNA binding activity. Is involved in several processes, including chromosome segregation\; embryo development\; and response to UV. Localizes to the cohesin complex and nuclear chromatin. Is expressed in the linker cell.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
HIM-1_emb1 25 11 24 0 15 24
HIM-1_emb2 186 Global proliferation rate changed Global proliferation rate changed 8 10 9
HIM-1_emb3 7 13 2 1 0 7
With cellular defects Yes Yes Yes Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

Abnormal division asynchrony
Not analyzed
Normal

Division asymmetry

Larger division asymmetry
Smaller division asymmetry
Not analyzed
Normal

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal