Summary

Gene name
hop-1
Sequence name
C18E3.8
Gene ID
WBGene00001985
Gene type
Protein Coding
RNAi library location
I-9G11
Gene information
Is an ortholog of human PSEN2 (presenilin 2). Is predicted to have endopeptidase activity. Is involved in several processes, including embryo development\; gonad development\; and nematode larval development. Human ortholog(s) of this gene are implicated in Alzheimer's disease 4 and dilated cardiomyopathy 1V.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
HOP-1_emb1 0 0 0 5 0 0
HOP-1_emb2 0 0 0 0 0 0
HOP-1_emb3 0 0 0 0 0 0
With cellular defects No No No Yes No No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

No defects