Summary

Gene name
hsf-1
Sequence name
Y53C10A.12
Gene ID
WBGene00002004
Gene type
Protein Coding
RNAi library location
I-6C09
Gene information
Is an ortholog of human HSF1 (heat shock transcription factor 1). Exhibits calmodulin binding activity\; promoter-specific chromatin binding activity\; and sequence-specific double-stranded DNA binding activity. Is involved in several processes, including dauer larval development\; defense response to Gram-negative bacterium\; and determination of adult lifespan. Localizes to the nuclear stress granule. Is expressed in several tissues, including the body wall musculature\; the hypodermis\; the intestine\; and the nervous system. Human ortholog(s) of this gene are implicated in cataract 5 multiple types.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
HSF-1_emb1 2 7 1 1 0 0
HSF-1_emb2 0 0 0 0 0 1
HSF-1_emb3 0 4 0 0 3 0
With cellular defects No Yes No No Yes No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

Abnormal division asynchrony
Not analyzed
Normal

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

No defects