Summary

Gene name
let-381
Sequence name
F26B1.7
Gene ID
WBGene00002601
Gene type
Protein Coding
RNAi library location
I-3C19
Gene information
Is an ortholog of human FOXF1 (forkhead box F1) and FOXF2 (forkhead box F2). Exhibits sequence-specific DNA binding activity. Is involved in mesodermal cell fate specification\; nematode larval development\; and positive regulation of mesodermal cell fate specification. Localizes to the nucleus. Is expressed in the M.dlp\; the M.drp\; the body wall muscle cell\; and the coelomocyte. Human ortholog(s) of this gene are implicated in persistent fetal circulation syndrome.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
LET-381_emb1 0 0 0 0 0 0
LET-381_emb2 0 2 1 0 0 0
LET-381_emb3 0 0 0 0 0 0
With cellular defects No No No No No No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

No defects