Summary

Gene name
msh-6
Sequence name
Y47G6A_242.c
Gene ID
WBGene00003422
Gene type
Protein Coding
RNAi library location
I-7N01
Gene information
Is an ortholog of human MSH6 (mutS homolog 6). Is predicted to contribute to ADP binding activity\; MutLalpha complex binding activity\; and mismatched DNA binding activity. Is involved in maintenance of DNA repeat elements and mismatch repair. Is used to study Lynch syndrome.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
MSH-6_emb1 23 145 3 0 2 0
MSH-6_emb2 0 0 0 0 0 0
MSH-6_emb3 0 0 0 0 1 0
With cellular defects No Yes Yes No No No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

Abnormal division asynchrony
Not analyzed
Normal

Division asymmetry

Larger division asymmetry
Smaller division asymmetry
Not analyzed
Normal

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

No defects