Summary

Gene name
mus-101
Sequence name
F37D6.1
Gene ID
WBGene00009507
Gene type
Protein Coding
RNAi library location
I-5C02
Gene information
Is an ortholog of human TOPBP1 (DNA topoisomerase II binding protein 1). Is involved in several processes, including DNA-dependent DNA replication\; cellular response to DNA damage stimulus\; and embryo development.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
MUS-101_emb1 176 Global proliferation rate changed Global proliferation rate changed 0 2 0
MUS-101_emb2 86 41 2 0 2 0
MUS-101_emb3 288 Global proliferation rate changed Global proliferation rate changed 0 8 4
With cellular defects Yes Yes No No Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

Abnormal division asynchrony
Not analyzed
Normal

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal