Summary

Gene name
nduf-6
Sequence name
F22D6.4
Gene ID
WBGene00009051
Gene type
Protein Coding
RNAi library location
I-3O24
Gene information
Is an ortholog of human NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6). Is involved in mitochondrial electron transport, NADH to ubiquinone and response to drug. Localizes to the mitochondrion. Human ortholog(s) of this gene are implicated in mitochondrial complex I deficiency.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A/P)		 Cell
position		 Phenotype
detection
NDUF-6_emb1 353 Global proliferation rate changed Global proliferation rate changed 20 0 0
NDUF-6_emb2 242 Global proliferation rate changed Global proliferation rate changed 29 1 0
NDUF-6_emb3 44 Global proliferation rate changed Global proliferation rate changed 9 21 78
With cellular defects Yes No No Yes Yes Yes

Early embryonic arrest

Arrest embryo: NDUF-6_emb4, NDUF-6_emb5

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry(A/P)

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle(A/P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal