Summary

Gene name
nhr-69
Sequence name
T23H4.2
Gene ID
WBGene00003659
Gene type
Protein Coding
RNAi library location
I-4N18
Gene information
Is an ortholog of human HNF4A (hepatocyte nuclear factor 4 alpha) and HNF4G (hepatocyte nuclear factor 4 gamma). Exhibits SMAD binding activity and steroid hormone binding activity. Is involved in negative regulation of transcription by RNA polymerase II. Localizes to the nucleus. Is expressed in the alimentary system\; the epithelial system\; and the nervous system. Human ortholog(s) of this gene are implicated in maturity-onset diabetes of the young type 1 and type 2 diabetes mellitus.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
NHR-69_emb1 0 0 0 0 1 0
NHR-69_emb2 0 0 0 0 1 1
NHR-69_emb3 0 0 0 0 0 0
With cellular defects No No No No No No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

No defects