Summary

Gene name
nkb-1
Sequence name
C17E4.9
Gene ID
WBGene00007646
Gene type
Protein Coding
RNAi library location
I-4L21
Gene information
Is an ortholog of human ATP1B1 (ATPase Na+\/K+ transporting subunit beta 1)\; ATP1B2 (ATPase Na+\/K+ transporting subunit beta 2)\; and ATP1B3 (ATPase Na+\/K+ transporting subunit beta 3). Is predicted to contribute to sodium:potassium-exchanging ATPase activity. Is expressed in the muscle cell and the nervous system. Human ortholog(s) of this gene are implicated in essential hypertension.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A/P)		 Cell
position		 Phenotype
detection
NKB-1_emb1 353 Global proliferation rate changed Global proliferation rate changed 6 11 17
NKB-1_emb2 351 Global proliferation rate changed Global proliferation rate changed 3 2 6
With cellular defects Yes No No Yes Yes Yes

Early embryonic arrest

Arrest embryo: NKB-1_emb3

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry(A/P)

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle(A/P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal