Summary

Gene name
npp-14
Sequence name
C03D6.4
Gene ID
WBGene00003800
Gene type
Protein Coding
RNAi library location
I-4F22
Gene information
Is an ortholog of human NUP214 (nucleoporin 214). Exhibits caspase binding activity. Is involved in inhibition of cysteine-type endopeptidase activity involved in apoptotic process and negative regulation of execution phase of apoptosis. Human ortholog(s) of this gene are implicated in acute lymphocytic leukemia.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
NPP-14_emb1 0 0 0 1 0 0
NPP-14_emb2 0 0 0 0 0 0
NPP-14_emb3 0 0 0 0 0 0
With cellular defects No No No No No No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

No defects