Summary

Gene name
par-6
Sequence name
T26E3.3
Gene ID
WBGene00003921
Gene type
Protein Coding
RNAi library location
I-6M10
Gene information
Is an ortholog of human PARD6A (par-6 family cell polarity regulator alpha)\; PARD6B (par-6 family cell polarity regulator beta)\; and PARD6G (par-6 family cell polarity regulator gamma). Exhibits Rho GTPase binding activity and protein kinase C binding activity. Is involved in several processes, including cell adhesion\; establishment of mitotic spindle localization\; and establishment or maintenance of cell polarity. Localizes to the P granule\; cell cortex\; and integral component of membrane. Is expressed in several tissues, including the ABa\; the ABp\; the excretory cell\; the germline blastomere\; and the somatic blastomere.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
PAR-6_emb1 153 180 77 85 161 674
PAR-6_emb2 141 350 66 81 176 696
PAR-6_emb3 137 186 78 83 171 689
With cellular defects Yes Yes Yes Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

Abnormal division asynchrony
Not analyzed
Normal

Division asymmetry

Larger division asymmetry
Smaller division asymmetry
Not analyzed
Normal

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal