Summary

Gene name
pash-1
Sequence name
T22A3.7
Gene ID
WBGene00011908
Gene type
Protein Coding
RNAi library location
I-5G22
Gene information
Is an ortholog of human DGCR8 (DGCR8 microprocessor complex subunit). Is predicted to contribute to ribonuclease III activity. Is involved in several processes, including primary miRNA processing\; regulation of development, heterochronic\; and regulation of epidermal cell differentiation. Is expressed in the head\; the hypodermis\; the intestine\; the marginal cell\; and the pharyngeal muscle cell. Is used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene are implicated in velocardiofacial syndrome.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
PASH-1_emb1 0 0 0 0 1 0
PASH-1_emb2 0 0 1 0 0 0
PASH-1_emb3 0 0 0 0 0 0
With cellular defects No No No No No No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

No defects