Summary

Gene name
pgrn-1
Sequence name
T22H2.6
Gene ID
WBGene00011936
Gene type
Protein Coding
RNAi library location
I-5J18
Gene information
Is an ortholog of human GRN (granulin precursor). Is expressed in the coelomocyte\; the nervous system\; and the pseudocoelom. Is used to study frontotemporal dementia. Human ortholog(s) of this gene are implicated in Grn-related frontotemporal lobar degeneration with Tdp43 inclusions and neuronal ceroid lipofuscinosis 11. Is predicted to encode a protein with the following domains: Granulin\; Granulin superfamily\; and Granulin family.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
PGRN-1_emb1 0 0 0 0 0 0
PGRN-1_emb2 0 0 0 2 0 0
With cellular defects No No No No No No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

No defects