Summary

Gene name
png-1
Sequence name
Y53H1C.a
Gene ID
WBGene00010160
Gene type
Protein Coding
RNAi library location
I-5P05
Gene information
Is an ortholog of human NGLY1 (N-glycanase 1). Exhibits peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity\; protein disulfide oxidoreductase activity\; and protein-disulfide reductase activity. Is involved in cell redox homeostasis\; cellular protein metabolic process\; and negative regulation of collateral sprouting. Localizes to the cytoplasm. Is expressed in the body wall musculature\; the gonad\; the nervous system\; the pharynx\; and the vulva. Human ortholog(s) of this gene are implicated in NGLY1-deficiency.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
PNG-1_emb1 0 0 0 0 0 0
PNG-1_emb2 0 0 1 0 0 0
With cellular defects No No No No No No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

No defects