Summary

Gene name
prp-31
Sequence name
Y110A7A.m
Gene ID
WBGene00022458
Gene type
Protein Coding
RNAi library location
I-2E12
Gene information
Is an ortholog of human PRPF31 (pre-mRNA processing factor 31). Human ortholog(s) of this gene are implicated in retinitis pigmentosa 11. Human PRPF31 exhibits U4 snRNA binding activity\; U4atac snRNA binding activity\; and snRNP binding activity. Is predicted to encode a protein with the following domains: Nop domain\; NOSIC\; Prp31 C-terminal\; U4\/U6 small nuclear ribonucleoprotein Prp31\; Helix hairpin bin domain superfamily\; and Nop domain superfamily.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
PRP-31_emb1 182 Global proliferation rate changed Global proliferation rate changed 46 139 518
PRP-31_emb2 181 Global proliferation rate changed Global proliferation rate changed 31 108 477
With cellular defects Yes No No Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal