Summary

Gene name
ptr-2
Sequence name
C32E8.8
Gene ID
WBGene00004217
Gene type
Protein Coding
RNAi library location
I-1J07
Gene information
Is an ortholog of human PTCHD1 (patched domain containing 1)\; PTCHD3 (patched domain containing 3)\; and PTCHD4 (patched domain containing 4). Is predicted to have transmembrane transporter activity. Is involved in mitotic cytokinesis\; molting cycle\; and nematode male tail tip morphogenesis.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A/P)		 Cell
position		 Phenotype
detection
PTR-2_emb1 14 Global proliferation rate changed Global proliferation rate changed 0 9 16
PTR-2_emb2 16 Global proliferation rate changed Global proliferation rate changed 0 7 22
With cellular defects Yes No No No Yes Yes

Early embryonic arrest

Arrest embryo: PTR-2_emb3

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry(A/P)

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle(A/P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal