Summary

Gene name
rab-10
Sequence name
T23H2.5
Gene ID
WBGene00004273
Gene type
Protein Coding
RNAi library location
I-3G23
Gene information
Is an ortholog of human RAB10 (RAB10, member RAS oncogene family). Exhibits GTPase activating protein binding activity and ankyrin repeat binding activity. Is involved in several processes, including endocytic recycling\; negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process\; and positive regulation of establishment of protein localization. Localizes to the axon\; cytoplasm\; and neuronal cell body. Is expressed in several tissues, including the alimentary system\; the coelomocyte\; the epithelial system\; the gonad\; and the nervous system.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
RAB-10_emb1 182 Global proliferation rate changed Global proliferation rate changed 24 3 8
RAB-10_emb2 183 Global proliferation rate changed Global proliferation rate changed 27 2 1
With cellular defects Yes No No Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal