Summary

Gene name
rab-5
Sequence name
F26H9.6
Gene ID
WBGene00004268
Gene type
Protein Coding
RNAi library location
I-4J01
Gene information
Is an ortholog of human RAB5B. Exhibits GTPase activating protein binding activity and GTPase activity. Is involved in several processes, including apical protein localization\; embryo development\; and phagosome maturation involved in apoptotic cell clearance. Localizes to the cytoplasm and periciliary membrane compartment. Is expressed widely.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
RAB-5_emb1 147 Global proliferation rate changed Global proliferation rate changed 49 48 281
RAB-5_emb2 0 0 0 0 0 0
RAB-5_emb3 0 0 2 2 0 0
With cellular defects Yes No No Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal