Summary

Gene name
rab-8
Sequence name
D1037.4
Gene ID
WBGene00004272
Gene type
Protein Coding
RNAi library location
I-1F11
Gene information
Is an ortholog of human RAB8A (RAB8A, member RAS oncogene family) and RAB8B (RAB8B, member RAS oncogene family). Exhibits GTPase activating protein binding activity and ankyrin repeat binding activity. Is involved in several processes, including embryonic genitalia morphogenesis\; negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process\; and positive regulation of establishment of protein localization. Localizes to the apical plasma membrane and cytoplasm. Is expressed in the body wall musculature.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
RAB-8_emb1 0 0 0 1 1 20
RAB-8_emb2 0 4 0 0 2 0
RAB-8_emb3 0 0 0 0 2 0
With cellular defects No Yes No No No Yes

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

Abnormal division asynchrony
Not analyzed
Normal

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

Abnormal cell position
Not analyzed
Normal