Summary

Gene name
rtcb-1
Sequence name
F16A11.2
Gene ID
WBGene00008877
Gene type
Protein Coding
RNAi library location
I-4L03
Gene information
Is an ortholog of human RTCB (RNA 2',3'-cyclic phosphate and 5'-OH ligase). Exhibits RNA ligase (ATP) activity. Is involved in several processes, including IRE1-mediated unfolded protein response\; germ cell development\; and tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate. Localizes to the cytoplasm and nucleus. Is used to study Parkinson's disease.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
RTCB-1_emb1 0 0 0 0 1 4
RTCB-1_emb2 0 0 0 0 1 0
RTCB-1_emb3 0 0 0 0 0 0
With cellular defects No No No No No Yes

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

Abnormal cell position
Not analyzed
Normal