Summary

Gene name
sem-2
Sequence name
C32E12.5.1
Gene ID
WBGene00004771
Gene type
Protein Coding
RNAi library location
I-9B04
Gene information
Is an ortholog of human SOX11 (SRY-box 11)\; SOX12 (SRY-box 12)\; and SOX4 (SRY-box 4). Is predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Is involved in several processes, including cell fate specification\; positive regulation of mesodermal cell fate specification\; and positive regulation of oviposition. Localizes to the nucleus. Is expressed in several tissues, including MS\; the ABalaaaarl\; the ABalaaaarr\; the body wall muscle quadrant\; and the head. Human ortholog(s) of this gene are implicated in autosomal dominant non-syndromic intellectual disability 27.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
SEM-2_emb1 0 0 0 0 0 0
SEM-2_emb2 0 1 0 0 0 0
SEM-2_emb3 0 0 0 0 0 0
With cellular defects No No No No No No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

No defects