Summary

Gene name
skr-2
Sequence name
F46A9.4
Gene ID
WBGene00004808
Gene type
Protein Coding
RNAi library location
I-4N09
Gene information
Is an ortholog of human SKP1 (S-phase kinase associated protein 1). Is predicted to have ligase activity. Is involved in several processes, including embryo development\; establishment of mitotic spindle orientation\; and negative regulation of cell population proliferation. Localizes to the SCF ubiquitin ligase complex. Is expressed in the intestine.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
SKR-2_emb1 2 2 0 0 0 0
SKR-2_emb2 1 2 1 0 3 0
SKR-2_emb3 23 250 10 6 21 443
With cellular defects No Yes Yes Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

Abnormal division asynchrony
Not analyzed
Normal

Division asymmetry

Larger division asymmetry
Smaller division asymmetry
Not analyzed
Normal

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal