Summary

Gene name
smg-2
Sequence name
Y48G8AL.6
Gene ID
WBGene00004880
Gene type
Protein Coding
RNAi library location
I-9B02
Gene information
Is an ortholog of human UPF1 (UPF1 RNA helicase and ATPase). Exhibits protein phosphatase 2A binding activity. Is involved in RNA metabolic process\; embryonic genitalia morphogenesis\; and negative regulation of gene expression. Localizes to the cytoplasm and nucleus. Is expressed in the intestinal cell and the muscle cell.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
SMG-2_emb1 0 0 0 0 1 0
SMG-2_emb2 0 0 0 0 0 1
SMG-2_emb3 245 Global proliferation rate changed Global proliferation rate changed 5 3 0
With cellular defects Yes No No Yes Yes No

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

No defects