Summary

Gene name
smo-1
Sequence name
K12C11.2
Gene ID
WBGene00004888
Gene type
Protein Coding
RNAi library location
I-1O13
Gene information
Is an ortholog of human SUMO1 (small ubiquitin like modifier 1). Exhibits identical protein binding activity. Is involved in several processes, including embryo development\; mitotic sister chromatid segregation\; and multicellular organismal locomotion. Is expressed in the gonad\; the ventral nerve cord\; and the vulval precursor cell. Human ortholog(s) of this gene are implicated in orofacial cleft 10.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
SMO-1_emb1 233 Global proliferation rate changed Global proliferation rate changed 2 5 16
SMO-1_emb2 234 Global proliferation rate changed Global proliferation rate changed 5 5 22
SMO-1_emb3 208 Global proliferation rate changed Global proliferation rate changed 1 7 124
With cellular defects Yes No No Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal