Summary

Gene name
sur-6
Sequence name
F26E4.1
Gene ID
WBGene00006352
Gene type
Protein Coding
RNAi library location
I-4J16
Gene information
Is an ortholog of human PPP2R2A (protein phosphatase 2 regulatory subunit Balpha)\; PPP2R2B (protein phosphatase 2 regulatory subunit Bbeta)\; and PPP2R2D (protein phosphatase 2 regulatory subunit Bdelta). Is predicted to contribute to protein serine\/threonine phosphatase activity. Is involved in embryo development\; nematode larval development\; and positive regulation of vulval development. Human ortholog(s) of this gene are implicated in spinocerebellar ataxia type 12.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A/P)		 Cell
position		 Phenotype
detection
SUR-6_emb1 275 Global proliferation rate changed Global proliferation rate changed 42 89 553
With cellular defects Yes No No Yes Yes Yes

Early embryonic arrest

Arrest embryo: SUR-6_emb2, SUR-6_emb3

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry(A/P)

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle(A/P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal