Summary

Gene name
taf-1
Sequence name
W04A8.7
Gene ID
WBGene00006382
Gene type
Protein Coding
RNAi library location
I-7C07
Gene information
Is an ortholog of human TAF1 (TATA-box binding protein associated factor 1) and TAF1L (TATA-box binding protein associated factor 1 like). Is predicted to contribute to transcription regulatory region DNA binding activity. Is involved in embryo development and positive regulation of transcription by RNA polymerase II. Localizes to the nucleus. Human ortholog(s) of this gene are implicated in X-linked dystonia-parkinsonism.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
TAF-1_emb1 269 Global proliferation rate changed Global proliferation rate changed 37 41 425
TAF-1_emb2 261 Global proliferation rate changed Global proliferation rate changed 30 19 297
TAF-1_emb3 209 Global proliferation rate changed Global proliferation rate changed 10 6 58
With cellular defects Yes No No Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal