Summary

Gene name
taf-4
Sequence name
R119.6
Gene ID
WBGene00006385
Gene type
Protein Coding
RNAi library location
I-1E17
Gene information
Is an ortholog of human TAF4B. Is predicted to have DNA binding activity and transcription factor binding activity. Is involved in embryo development\; positive regulation of transcription by RNA polymerase II\; and regulation of mitotic cell cycle, embryonic. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene are implicated in azoospermia and spermatogenic failure 13.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
TAF-4_emb1 295 Global proliferation rate changed Global proliferation rate changed 45 84 541
TAF-4_emb2 281 Global proliferation rate changed Global proliferation rate changed 48 70 520
TAF-4_emb3 285 Global proliferation rate changed Global proliferation rate changed 41 56 479
With cellular defects Yes No No Yes Yes Yes

Cell Proliferation

Proliferation speed

Cell cycle length

Longer cell cycle length
Shorter cell cycle length
Not analyzed
Normal

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

Wild type tissue marker expression

Stable expression
Stable non-expression or partial expression

CND-1 expression

Gain of CND-1 expression
Loss of CND-1 expression
Normal

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

Abnormal cell position
Not analyzed
Normal