Is an ortholog of human UBR1 (ubiquitin protein ligase E3 component n-recognin 1) and UBR2 (ubiquitin protein ligase E3 component n-recognin 2). Exhibits ubiquitin conjugating enzyme binding activity. Is involved in negative regulation of glutamate metabolic process and regulation of backward locomotion. Is expressed in the body wall musculature\; the head\; the nervous system\; the pharynx\; and the seam cell. Human ortholog(s) of this gene are implicated in Johanson-Blizzard syndrome.