Summary

Gene name
ubr-1
Sequence name
C32E8.11
Gene ID
WBGene00016326
Gene type
Protein Coding
RNAi library location
I-1J13
Gene information
Is an ortholog of human UBR1 (ubiquitin protein ligase E3 component n-recognin 1) and UBR2 (ubiquitin protein ligase E3 component n-recognin 2). Exhibits ubiquitin conjugating enzyme binding activity. Is involved in negative regulation of glutamate metabolic process and regulation of backward locomotion. Is expressed in the body wall musculature\; the head\; the nervous system\; the pharynx\; and the seam cell. Human ortholog(s) of this gene are implicated in Johanson-Blizzard syndrome.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
UBR-1_emb1 0 0 1 0 1 1
UBR-1_emb2 0 0 0 0 0 0
UBR-1_emb3 0 1 0 0 2 0
UBR-1_emb4 0 0 0 0 0 0
With cellular defects No No No No No No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

No defects