Summary

Gene name
unc-37
Sequence name
W02D3.9
Gene ID
WBGene00006773
Gene type
Protein Coding
RNAi library location
I-9B08
Gene information
Is an ortholog of human TLE3 (TLE family member 3, transcriptional corepressor) and TLE4 (TLE family member 4, transcriptional corepressor). Exhibits transcription factor binding activity. Is involved in several processes, including chemical synaptic transmission\; regulation of axonogenesis\; and regulation of neurotransmitter levels. Localizes to the nucleus. Is expressed in several tissues, including the head and the tail.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
UNC-37_emb1 12 15 10 0 0 2
UNC-37_emb2 0 0 1 0 0 3
UNC-37_emb3 0 0 0 0 1 0
With cellular defects No Yes Yes No No Yes

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

Abnormal division asynchrony
Not analyzed
Normal

Division asymmetry

Larger division asymmetry
Smaller division asymmetry
Not analyzed
Normal

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

Abnormal cell position
Not analyzed
Normal