Summary

Gene name
unc-54
Sequence name
F11C3.3.1
Gene ID
WBGene00006789
Gene type
Protein Coding
RNAi library location
I-9B09
Gene information
Is an ortholog of human MYH4 (myosin heavy chain 4)\; MYH6 (myosin heavy chain 6)\; and MYH7 (myosin heavy chain 7). Exhibits actin filament binding activity and microfilament motor activity. Is involved in several processes, including inositol lipid-mediated signaling\; locomotion\; and muscle contraction. Localizes to the A band and striated muscle myosin thick filament. Is expressed in the anal depressor muscle\; the body wall musculature\; the head\; the vulval muscle\; and in the male. Human ortholog(s) of this gene are implicated in several diseases, including Carney complex\; intrinsic cardiomyopathy (multiple)\; and muscle tissue disease (multiple).

Lineage tracing results

Phenotype

Cell
cycle
Division
asynchrony
Division
asymmetry
CND-1
expression
Division
angle
(A-P)
Cell
position
Phenotypic
measurement
Phenotypic
detection
UNC-54_emb1 0 0 0 0 0 0
UNC-54_emb2 0 0 0 1 0 1
UNC-54_emb3 0 0 0 0 1 0
With cellular defects No No No No No No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

No defects

Relative cell position

No defects