Summary

Gene name
unc-73
Sequence name
F55C7.7
Gene ID
WBGene00006805
Gene type
Protein Coding
RNAi library location
I-1B20
Gene information
Is an ortholog of human KALRN (kalirin RhoGEF kinase) and TRIO (trio Rho guanine nucleotide exchange factor). Exhibits Rac guanyl-nucleotide exchange factor activity. Is involved in several processes, including engulfment of apoptotic cell\; generation of neurons\; and modulation of chemical synaptic transmission. Localizes to the axon\; cytoplasm\; and muscle cell projection. Is expressed in several tissues, including the epithelial system\; the nervous system\; the reproductive system\; the ventral cord blast cell\; and in the male. Is used to study epilepsy.

Lineage tracing results

Phenotype

Cell
cycle		 Division
asynchrony		 Division
asymmetry		 CND-1
expression		 Division
angle
(A-P)		 Cell
position		 Phenotypic
measurement		 Phenotypic
detection
UNC-73_emb1 0 0 0 0 5 1
UNC-73_emb2 0 0 0 0 0 0
UNC-73_emb3 0 0 0 0 2 0
With cellular defects No No No No Yes No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

No defects