Summary

Gene name
ztf-11
Sequence name
F52F12.6
Gene ID
WBGene00009939
Gene type
Protein Coding
RNAi library location
I-4P08
Gene information
Is an ortholog of human MYT1 (myelin transcription factor 1)\; MYT1L (myelin transcription factor 1 like)\; and ST18 (ST18 C2H2C-type zinc finger transcription factor). Is predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Is involved in nematode larval development. Is expressed in head neurons and the g1. Human ortholog(s) of this gene are implicated in autosomal dominant non-syndromic intellectual disability 39.

Lineage tracing results

Phenotype

Cell
cycle
Division
asynchrony
Division
asymmetry
CND-1
expression
Division
angle
(A-P)
Cell
position
Phenotypic
measurement
Phenotypic
detection
ZTF-11_emb1 1 1 0 0 0 1
ZTF-11_emb2 0 0 0 0 3 0
ZTF-11_emb3 0 0 0 0 1 1
With cellular defects No No No No Yes No

Cell Proliferation

Proliferation speed

Cell cycle length

No defects

Division asynchrony

No defects

Division asymmetry

No defects

Tissue Marker Expression (CND-1)

CND-1 expression

No defects

Morphogenesis

Division angle (A-P)

Larger division angle (A-P)
Smaller division angle (A-P)
Not analyzed
Normal

Relative cell position

No defects